Jesse Bisiwu impressed at Club Brugge's U16 and signed his first professional contract in January 2023. He has since progressed to Club NXT U23 and scored his first goal for Club A against Knokke during preparations for the 2024-2025 season.
Bisiwu went through Club Brugge's youth series and is considered a great talent. At the age of 15, he made his U23 debut in the Challenger Pro League, making him one of the youngest debutants in Belgian professional soccer. His contract runs until 2027.